WASHINGTON – Scientists have identified a member of a new class of hormones produced by body fat that they think could lead to fresh approaches to combat diabetes and other conditions related to obesity.
The hormone prevents the liver from accumulating fat and enhances toming from fat cells,” Hotamisligil said in a telephone interview.
One of its roles is to communicate with the liver and prevent it from accumulating fat, which can occur as people become obese, he said. It also encourages muscle to take up glucose from blood and dispose of it, he added.
It works almost as well as the hormone insulin at pushing sugar out of the blood, Hotamisligil said. Insulin regulates the absorption of sugar into the cells.
People with diabetes have blood sugar levels that are too high. Those with type 2 diabetes, the form closely related to obesity, are resistant to the effects of insulin or produce too little of it.
The researchers said that as body fat increases, less palmitoleate is produced. So in obese people, the beneficial functions of this hormone in controlling blood sugar levels and preventing fat accumulating in the liver would be diminished.
“When you need it the most, you produce the least,” Hotamisligil sa$180 billion in extra liquidity to calm panicked stock and money markets. Morgan Stanley was in deal talks with U.S. regional banking powerhouse Wachovia Corp, and negotiations advanced to a more formal stage, a source familiar with Morgan's plan said on Thursday.
U.S. examining Afghan war strategy, Gates says
LONDON (Reuters) – The Pentagon is taking a close look at its war strategy in Afghanistan in the face of rising violence from an increasingly complex insurgency, Defense Secretary Robert Gates said on Thursday. Gates declined to say if a formal or informal review had been launched but noted the United States had previously examined its strategy in Iraq – a review that resulted in major changes, including a boost in troop numbers.
Yemen arrests 30 after U.S. embassy attack
SANAA (Reuters) – Yemeni authorities have arrested 30 people suspected of belonging to al Qaeda following an attack on the heavily fortified U.S. embassy in Sanaa, a security source said on Thursday. Two suicide car bombs set off a series of explosions outside the embassy compound on Wednesday, killing 17 people including six attackers.
New Israeli leader Livni starts coalition talks
JERUSALEM (Reuters) – Israeli Foreign Minister Tzipi Livni began talks on forming a new coalition government on Thursday after edging home in a party leadership contest that set her on course to replace Ehud Olmert as prime minister. Among those she spoke with by telephone was U.S. Secretary of State Condoleezza Rice, who hopes Livni and Olmert can still clinch some form of peace deal with the Palestinians before the Bush administration quits the White House in just four months.
Rice says “bullying” Russia must be stopped
WASHINGTON (Reuters) – The West must stand up to “bullying” by Moscow and keep Russia from benefiting from its military move into Georgia, U.S. Secretary of State Condoleezza Rice said in a harshly-worded speech on Thursday. In her first major address on Russia since its incursion into Georgia last month, Rice described Moscow as increasingly authoritarian and aggressive and said its aims in the Caucasus state would be frustrated.
Russia envoy warns NATO on air space to Afghanistan
KABUL (Reuters) – Russia threatened to block NATO from using its air space for operations in Afghanistan if member states did not stop “hostile” policies toward Moscow, the Kremlin's top diplomat in Kabul said. “(Russian air space) is still open, but if the NATO countries continue to their hostile policies with regard to Russia, definitely this issue will happen,” Zamir Kabulov told BBC radio in an interview aired on Thursday.
Iran vows no nuclear retreat despite sanctions threat
TEHRAN (Reuters) – President Mahmoud Ahmadinejad said on Thursday Iran would not halt sensitive nuclear work the West suspects is aimed at making bombs and brushed aside threats of more sanctions. Ahmadinejad, who is due to attend the U.N.'s general assembly debate next week, also said he was willing to meet with both U.S. presidential candidates while in New York.
Zimbabwe cabinet talks deadlocked over posts
HARARE (Reuters) – Zimbabwean President Robert Mugabe and prime minister designate Morgan Tsvangirai are deadlocked over appointing cabinet ministers after reaching a power-sharing agreement, an MDC party official said on Thursday. Mugabe signed the agreement with Tsvangirai on Monday, relinquishing some powers for the first time in nearly three decades of rule under pressure from regional leaders and a growing economic crisis.
U.S. soldier sentenced over killings of Iraqis
BERLIN (Reuters) – A U.S. soldier who admitted involvement in the shooting of detainees in Iraq early last year has been sentenced to seven months in jail and will be dishonorably discharged, the army said on Thursday. Specialist Belmor Ramos, 23, pleaded guilty at a court martial in Germany to charges of conspiracy to commit premeditated murder. He agreed to testify in the trials of other soldiers involved, the army said in a statement.
Pakistan says not informed of U.S. missile strike
ISLAMABAD (Reuters) – The United States did not inform Pakistan about a missile strike on militants hours after the top U.S. military officer said the United States would respect Pakistan's sovereignty, Pakistan's foreign minister said. The United States, frustrated by an intensifying Taliban insurgency in Afghanistan, has stepped up attacks on militants in Pakistan with six missile attacks by pilotless drones and a helicopter-borne ground assault this month.